Our pre-arrayed human and mouse sub-libraries provide state-of-the-art silencing triggers to study the function of an entire protein family, or biological process, such as epigenetics, ubiquitin conjugation, ion channels, membrane transporters, nuclear receptors, receptors in general, transcription factors, transporters, proteases, kinases, and phosphatases. All of these sub-libraries are druggable.
Exemplary human druggable sub-libraries with their targets are listed below. For other, or custom sub-libraries please inquire.
esiRNA ID | Gene Name | Gene Description | Ensembl ID | |
HU-02595-1 | AR | androgen receptor | ENSG00000169083 | |
HU-14165-1 | ESR1 | estrogen receptor 1 | ENSG00000091831 | |
HU-90008-1 | ESR2 | Estrogen receptor 2 (ER beta) | ENSG00000140009 | |
HU-10728-1 | ESRRA | estrogen-related receptor alpha | ENSG00000173153 | |
HU-04474-1 | ESRRB | estrogen-related receptor beta | ENSG00000119715 | |
HU-90009-1 | ESRRG | Estrogen-related receptor gamma | ENSG00000196482 | |
HU-06674-1 | HNF4A | hepatocyte nuclear factor 4, alpha | ENSG00000101076 | |
HU-09225-1 | HNF4G | hepatocyte nuclear factor 4, gamma | ENSG00000164749 | |
HU-12211-1 | NR0B1 | nuclear receptor subfamily 0, group B, member 1 | ENSG00000169297 | |
HU-15663-1 | NR0B2 | nuclear receptor subfamily 0, group B, member 2 | ENSG00000131910 | |
HU-14341-1 | NR1D1 | nuclear receptor subfamily 1, group D, member 1 | ENSG00000126368 | |
HU-04844-1 | NR1D2 | nuclear receptor subfamily 1, group D, member 2 | ENSG00000174738 | |
HU-01834-1 | NR1H2 | nuclear receptor subfamily 1, group H, member 2 | ENSG00000131408 | |
HU-13463-1 | NR1H3 | nuclear receptor subfamily 1, group H, member 3 | ENSG00000025434 | |
HU-13316-1 | NR1H4 | nuclear receptor subfamily 1, group H, member 4 | ENSG00000012504 | |
HU-08147-1 | NR1I2 | nuclear receptor subfamily 1, group I, member 2 | ENSG00000144852 | |
HU-13906-1 | NR1I3 | nuclear receptor subfamily 1, group I, member 3 | ENSG00000143257 | |
HU-08565-1 | NR2C1 | nuclear receptor subfamily 2, group C, member 1 | ENSG00000120798 | |
HU-04202-1 | NR2C2 | nuclear receptor subfamily 2, group C, member 2 | ENSG00000177463 | |
HU-13025-1 | NR2E1 | nuclear receptor subfamily 2, group E, member 1 | ENSG00000112333 | |
HU-13277-1 | NR2E3 | nuclear receptor subfamily 2, group E, member 3 | ENSG00000031544 | |
HU-90006-1 | NR2F1 | nuclear receptor subfamily 2, group F, member 1 | ENSG00000175745 | |
HU-02364-1 | NR2F2 | nuclear receptor subfamily 2, group F, member 2 | ENSG00000185551 | |
HU-90007-1 | NR2F6 | Nuclear receptor subfamily 2, group F, member 6 | ENSG00000160113 | |
HU-06800-1 | NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | ENSG00000113580 | |
HU-08859-1 | NR3C2 | nuclear receptor subfamily 3, group C, member 2 | ENSG00000151623 | |
HU-15723-1 | NR4A1 | nuclear receptor subfamily 4, group A, member 1 | ENSG00000123358 | |
HU-00873-1 | NR4A2 | nuclear receptor subfamily 4, group A, member 2 | ENSG00000153234 | |
HU-90011-1 | NR4A3 | Nuclear receptor subfamily 4, group A, member 3 | ENSG00000119508 | |
HU-14253-1 | NR5A1 | nuclear receptor subfamily 5, group A, member 1 | ENSG00000136931 | |
HU-06607-1 | NR5A2 | nuclear receptor subfamily 5, group A, member 2 | ENSG00000116833 | |
HU-05095-1 | NR6A1 | nuclear receptor subfamily 6, group A, member 1 | ENSG00000148200 | |
HU-90010-1 | PGR | Progesterone receptor | ENSG00000082175 | |
HU-15182-1 | PPARA | peroxisome proliferator-activated receptor alpha | ENSG00000186951 | |
HU-05879-1 | PPARD | peroxisome proliferator-activated receptor delta | ENSG00000112033 | |
HU-09771-1 | PPARG | peroxisome proliferator-activated receptor gamma | ENSG00000132170 | |
HU-06427-1 | RARA | retinoic acid receptor, alpha | ENSG00000131759 | |
HU-06658-1 | RARB | retinoic acid receptor, beta | ENSG00000077092 | |
HU-15819-1 | RARG | retinoic acid receptor, gamma | ENSG00000172819 | |
HU-07274-1 | RORA | RAR-related orphan receptor A | ENSG00000069667 | |
HU-10108-1 | RORB | RAR-related orphan receptor B | ENSG00000198963 | |
HU-09384-1 | RORC | RAR-related orphan receptor C | ENSG00000143365 | |
HU-15326-1 | RXRA | retinoid X receptor, alpha | ENSG00000186350 | |
HU-21995-1 | RXRB | retinoid X receptor, beta | ENSG00000204231 | |
HU-06498-1 | RXRG | retinoid X receptor, gamma | ENSG00000143171 | |
HU-01376-1 | THRA | thyroid hormone receptor, alpha | ENSG00000126351 | |
HU-08346-1 | THRB | thyroid hormone receptor, beta | ENSG00000151090 | |
HU-01044-1 | VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | ENSG00000111424 |